Artificial protein injected to restore neural function successfully in mouse experiments

Artificial Protein Injected to Restore Neural Function Successful in Mouse Experiment September 2 at 3:48 AM

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A group such as Keio University announced that they had succeeded in experimenting with mice to restore the function of broken nerves by injecting artificially created proteins. The group said, “We would like to further confirm safety and effectiveness, which will lead to the development of therapeutic drugs such as spinal cord injury and Alzheimer’s disease.”

This research was conducted by Professor Yusuke Shinozaki of Keio University and a group from Aichi Medical University.

The group focused on a special molecule that connects neurons together in a part called synapses, where nerve cells transmit information, and synthesized an artificial protein called “CPTX” based on this molecule.

When this protein was injected into mice cause of spinal cord injury, the movement of the hind legs, which had been damaged, improved to about 80% of normal mice and was able to walk.

They also found that injecting this protein into the brains of mice that reproduce Alzheimer’s disease, which damages nerves in the brain, improves memory.

The group said the protein is used to restore neural signaling circuits damaged by injuries and diseases.

Professor Shinozaki, who conducted the research, said, “In the future, after further confirming the safety and effectiveness, we would like to lead to the treatment of people, such as spinal cord injury and Alzheimer’s disease, which are difficult to treat.”